ALLERGIC DISORDERS… Antihistaminics in Urticaria 19 Mar 202011 Mar 2020 Depending on the duration of clinical symptoms (the time since the first episode of urticarial wheals), urticaria can be classified as acute (up to 6 weeks) or chronic (over 6 weeks). In acute urticaria second-generation antihistamines are the first choice. For refractory cases, use a combination of H1 and H2…