Dr Silky Jain, Pediatric Haematology-Oncologist & BMT Physician – Pediatric Practice… Pearls for your Pediatric Office Practice

Diseases of the Blood…

Megaloblastic anemia treatment pearls

11 Sep 20228 Sep 2022

Vitamin B12 supplementation The schedules and dosages of vitamin B12 treatment are widely variable and there is no consensus on it. The cause of megaloblastic anemia and the response to…

Diseases of the Blood…

Biochemical markers of B12 deficiency

4 Sep 20224 Sep 2022

Previous Post : Vitamin B12 levels Serum Holo-Transcobalamin Vitamin B12 bound to Transcobalamin = Holo-TC Represents 10 -30% of total Vitamin B12 present in serum Cells take up Holo-TC via…

Diseases of the Blood…

Vitamin B12 Levels

28 Aug 202228 Aug 2022

WHO DefinitionsVitamin B12 cut-offB12 adequacy> 221 pmol/LLow B12148 -221 pmol/LB12 deficiency< 148 pmol/L Pitfalls of Serum Vitamin B12 Neither sensitive, nor specificVitamin B12 levels mostly reflect the predominant but functionally…