PEDIATRIC DRUG THERAPY… Esomeprazole 18 Sep 202217 Sep 2022 Usage in Neonatal age group GERD Routine use is not recommended in preterm neonates Term and preterm neonates: Oral: 0.5 mg/kg/dose once daily. DURATION of therapy in symptomatic GERD : Guidelines…
Diseases of the Blood… Megaloblastic anemia treatment pearls 11 Sep 20228 Sep 2022 Vitamin B12 supplementation The schedules and dosages of vitamin B12 treatment are widely variable and there is no consensus on it. The cause of megaloblastic anemia and the response to…
Diseases of the Blood… Biochemical markers of B12 deficiency 4 Sep 20224 Sep 2022 Previous Post : Vitamin B12 levels Serum Holo-Transcobalamin Vitamin B12 bound to Transcobalamin = Holo-TC Represents 10 -30% of total Vitamin B12 present in serum Cells take up Holo-TC via…
Diseases of the Blood… Vitamin B12 Levels 28 Aug 202228 Aug 2022 WHO DefinitionsVitamin B12 cut-offB12 adequacy> 221 pmol/LLow B12148 -221 pmol/LB12 deficiency< 148 pmol/L Pitfalls of Serum Vitamin B12 Neither sensitive, nor specificVitamin B12 levels mostly reflect the predominant but functionally…
INFECTIOUS DISEASES… When it is NOT congenital syphilis 21 Aug 202220 Aug 2022 Congenital syphilis is unlikely in following scenario- Any neonate who has a normal physical examination and a serum quantitative nontreponemal serologic titer (VDRL) equal to or less than four-fold the…
The Fetus and the Neonatal Infant APT Test For Swallowed Maternal Blood 18 Aug 202216 Aug 2022 In a newborn infant with rectal bleeding or a blood streaked gastric aspirate, we need to determine whether the blood originated from infant’s gut or whether it’s the swallowed maternal…
Antimicrobials… Trimethoprim-Sulfamethoxazole 14 Aug 202214 Aug 2022 Always used as a fixed dose combination of Trimethoprim-Sulfamethoxazole in ratio of 1:5. Dose of Trimethoprim(TMP) is used for calculation purposes. Mild to Moderate Infections 4 mg TMP/kg/dose PO - 12…
Anti Parasitic Drugs… Permethrin- Therapeutic uses 7 Aug 202212 Aug 2022 Scabies Infants ≥2 months, Children, and Adolescents: Topical Permethrin 5% cream : Apply and massage in cream from head to toe (average adult requires 30 g); leave on for 8 to 14…
Respiratory System… Role of a sleep study in pediatric Obstructive Sleep Apnea Syndrome 31 Jul 20225 Aug 2022 Obstructive Sleep Apnea Syndrome(OSAS) is a disorder of breathing during sleep characterized by prolonged partial upper airway obstruction and/or intermittent complete obstruction (obstructive apnea). This disrupts normal ventilation during sleep &…
Rheumatic, Connective Tissue and Collagen Vascular Diseases of Childhood When To Suspect Vasculitis In Children 28 Jul 202226 Jul 2022 Vasculitis should be suspected in patients with unexplained fever, weight loss, skin rashes; especially when associated with high ESR and CRP. The most common primary vasculitides in children are Henoch-Schonlein purpura (HSP)…