Diagnostic Modalities… Role of haemogram(CBC) in Primary Immunodeficiency (PID) 29 Aug 202127 Aug 2021 Primary immunodeficiencies (PID) include >200 inherited disorders that affect the development and function of lymphocytes, neutrophils, eosinophils or monocytes. The first step in diagnosing a primary immunodeficiency is to suspect it.…
Immunological Disorders… Primary Immunodeficiencies Disorders (PID) 26 Aug 202125 Aug 2021 These congenital disorders are defects in the various pathways of immune system which may present in the first year of life or later in childhood. The immune system is an…
Diseases of the Blood… Hemophagocytic Lymphohistiocytosis (HLH) 14 Jan 202111 Jan 2021 Hemophagocytic lymphohistiocytosis is a terminology that is being encountered frequently in the past few years. It is a pathological entity where uncontrolled inflammation results in activation of lymphocytes. Activated T…
Immunological Disorders… When to suspect A Primary Immunodeficiency 1 Nov 2020 Primary immunodeficiencies are to be suspected in any patient with Unusual susceptibility for infections, Severe or early onset autoimmunity and Susceptibility to malignancies. Initially only patients with susceptibility towards infections were evaluated…
Immunological Disorders… Periodic Fever Aphthous Stomatitis Pharyngitis Adenitis Syndrome PFAPA Part 2 4 Jun 202031 May 2020 Continued from previous post…(Clinical Symptoms & Diagnosis click to read) WHEN IT IS NOT PFAPA Patients should be evaluated for the following features since the presence of any of them…
Immunological Disorders… Periodic Fever Aphthous Stomatitis Pharyngitis Adenitis – PFAPA Syndrome: Part 1 31 May 202031 May 2020 PFAPA is a common autoinflammatory syndrome in childhood. The onset is usually before 5 years of age and attacks typically cease by 10 years of age in most patients, though a minority…
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