Desquamated epithelial cells that are trapped under the foreskin are referred to as smegma. In boys without a fully retractable foreskin, smegma may form white lumps under the foreskin, often referred to as preputial cysts. They are also referred to as “Smegma Pearls”.
Preputial cysts are benign and usually are located around the corona. They aid in the process of separation between the foreskin and the glans penis, and are extruded once the foreskin becomes more retractable.
Preputial cysts can also be seen around clitoris in females.
No treatment is required for preputial cysts.