Rheumatic, Connective Tissue and Collagen Vascular Diseases of Childhood When To Suspect Vasculitis In Children 28 Jul 202226 Jul 2022 Vasculitis should be suspected in patients with unexplained fever, weight loss, skin rashes; especially when associated with high ESR and CRP. The most common primary vasculitides in children are Henoch-Schonlein purpura (HSP)…
Rheumatic, Connective Tissue and Collagen Vascular Diseases of Childhood Neonatal Lupus- A Missed Diagnosis 24 Jul 202222 Jul 2022 Neonatal lupus is caused by autoantibodies crossing the placenta from the mother to the fetus. Mothers of the affected infants maybe asymptomatic at the time of delivery. Most common presentation…
Laboratory Tests… Analysing Serum Ferritin 7 Oct 20215 Oct 2021 Serum ferritin is an acute phase reactant, which can be elevated due to any acute infection, rheumatological illness or infiltrative disease. Elevated serum ferritin is seen in rheumatological illnesses such…
Evaluation of Arthritis… Systemic Onset Juvenile Idiopathic Arthritis SOJIA 19 Sep 202117 Sep 2021 SOJIA is characterized by fever which is documented to be quotidian for at least 3 days and lasts for 2 weeks. It can be seen in all age groups. Child…
Evaluation of Arthritis… Rheumatoid Factor 8 Aug 20213 Aug 2021 Rheumatoid Factor (RF) is an antibody(of IgM class) which is directed against the Fc portion of IgG. RF helps to classify patients with polyarticular juvenile idiopathic arthritis(PJIA) into RF positive…
Reactive arthritis… Reactive Arthritis 3 Jun 202130 May 2021 It is an inflammatory joint disease which is caused by an extraarticular infection. However, there is absence of bacteria in the joint. Reactive arthritis usually occurs one to four weeks…
Laboratory Tests… Antinuclear Antibody-ANA 18 Feb 202118 Feb 2021 Antinuclear antibodies(ANA) are autoantibodies which recognize cellular antigens found predominantly(although not exclusively), in the cell nucleus. A positive ANA of 1:160 or more is highly suggestive of autoimmune diseases such…
Henoch Scholein Purpura… Henoch Scholein Purpura 10 Jan 202110 Jan 2021 It is the most common primary systemic vasculitis in children. Diagnosis requires the presence of purpura or petechiae with lower limb predominance with one of the following four- Abdominal pain Arthritis…
Immunological Disorders… Periodic Fever Aphthous Stomatitis Pharyngitis Adenitis Syndrome PFAPA Part 2 4 Jun 202031 May 2020 Continued from previous post…(Clinical Symptoms & Diagnosis click to read) WHEN IT IS NOT PFAPA Patients should be evaluated for the following features since the presence of any of them…
Immunological Disorders… Periodic Fever Aphthous Stomatitis Pharyngitis Adenitis – PFAPA Syndrome: Part 1 31 May 202031 May 2020 PFAPA is a common autoinflammatory syndrome in childhood. The onset is usually before 5 years of age and attacks typically cease by 10 years of age in most patients, though a minority…
Pediatric Practice... Pearls for your Pediatric Office Practice 