Continued from Previous Post: Role of HIDA Scan in Cholestasis
Treatment of neonatal cholestasis depends on underlying etiology.
- Biliary atresia needs early Kasai porto-enterostomy, before the age of 3 months
- Galactosemia needs lactose free diet.
- Nutrition and supplementation of vitamins play an important role in neonatal cholestasis irrespective of the underlying cause. Supplementation of fat soluble vitamins (A, D, E, K) is important. Usually 1.5- 2 times of the Daily recommended doses are used for most of the Vitamins and minerals/nutrients.
DOSES OF VITAMINS AND MINERALS IN CHOLESTASIS
Vit A | Oral | 5,000-25,000 IU/day |
Vit D | Oral | 400- 1,200 IU/day |
Vit E | Oral(Cap Evion 200/400IU) | 50-400 IU/day or 15-25 IU/kg/day |
Vit K | Parenteral (im or iv) | 5mg monthly |
Water soluble Vitamins | Oral | 1.5 -2 times RDA |
Calcium | Oral | 20-100 mg/kg/day |
Phosphorus | Oral | 25-50 mg/kg/day |
Zinc | Oral | 1 mg/kg/day |
Magnesium | Oral | 1 meq/kg/day |
Elemental Iron | Oral | 5-6 mg/kg/day |