It is the most common non-epileptic movement disorder in neonatal period.
Generalized symmetric, rhythmic movements of chin and/or extremities that resemble tremor.
It is stimulus sensitive; increased with crying. It can be precipitated by startle and suppressed by gentle passive flexion of the limb.
It disappears shortly after birth, but can persist for months.
Persistent jitteriness has been associated with hypoxic-ischemic injury, intracerebral hemorrhage, hypocalcemia, hypoglycemia, hypomagnesemia, and drug withdrawal, which may produce neuronal hyperirritability.
Idiopathic jitteriness is usually associated with normal development and neurologic outcome. No treatment needed for these cases.
The outcome of infants with symptomatic jitteriness depends on the underlying cause.